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1: Cutis. 1984 Oct;34(4):366-73.Links

Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride.

McCune MA, Perry HO, Muller SA, O'Fallon WM.

In a prospective, randomized, double-blind, placebo-controlled, cross-over study of forty-one patients we found that oral ingestion of 1,248 mg a day of L-Lysine monohydrochloride shows evidence of decreasing the recurrence rate of herpes simplex attacks in nonimmunocompromised hosts. A dose of 624 mg a day was not effective. L-Lysine may also be capable of decreasing the severity of symptoms associated with recurrences. Neither dosage showed any evidence of shortening the healing time compared to placebo.

PMID: 6435961 [PubMed - indexed for MEDLINE]