Display Settings:

Format

Send to:

Choose Destination
Am J Med Genet. 1984 May;18(1):135-46.

A comparison of three affected-sib-pair scoring methods to detect HLA-linked disease susceptibility genes.

Abstract

Two widely used affected-sib-pair scoring procedures (the Green and Woodrow [1977] procedure, and the method of forming all possible affected-sib-pairs) are compared with a new method for their relative efficiency in detecting the presence of an HLA-linked disease susceptibility gene. Their relative performance is investigated by extensive computer simulations over a large number of disease transmission models. On the average, the new procedure appears to outperform the Green and Woodrow method and the "all-possible-pairs" method.

PMID:
6430084
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk