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JAMA. 1984 Jul 13;252(2):235-9.

A cost-effectiveness analysis of alternative approaches for long-term treatment of proximal venous thrombosis.


Recent data from randomized trials have provided a clear understanding of the effectiveness and safety of differing long-term anticoagulant therapies for proximal vein thrombosis. An issue that has not been addressed is their cost-effectiveness. We have performed a cost-effectiveness analysis to rank alternative approaches for long-term therapy. Less intense oral anticoagulant therapy using warfarin sodium is the most cost-effective approach and is preferred in the majority of patients.

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