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J Pharm Sci. 1978 Apr;67(4):560-1.

Drug absorption VIII: Kinetics of GI absorption of methotrexate.

Abstract

The absorption of methotrexate from the lumen of the rat small intestine, in situ, was found to obey Michaelis--Menten kinetics. The values of Vmax and Km for the absorption process were 4.78 X 10(-7) M/min and 1.49 X 10(-5) M, respectively.

PMID:
641772
[PubMed - indexed for MEDLINE]
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