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Nature. 1984 Aug 16-22;310(5978):549-54.

Developmental biology of a neural cell adhesion molecule.

Abstract

A membrane glycoprotein isolated from embryonic brain has been shown to be a ligand in the formation of cell-cell bonds. The molecule, called neural cell adhesion molecule (N-CAM), participates in several aspects of neural development, including the formation of plexiform layers, neurite fasciculation and nerve-muscle interactions. Experiments in vivo indicate that N-CAM-mediated adhesion is essential to the orderly assembly of the visual system.

PMID:
6379469
[PubMed - indexed for MEDLINE]
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