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Biochem J. 1983 Dec 1;215(3):465-9.

Identification of low-frequency modes in protein molecules.

Abstract

It is demonstrated that the observed low-frequency motions with wave numbers of 22 cm-1 and 25 cm-1 for insulin and lysozyme respectively originate from the accordion-like motions of the principal helices therein. The calculated results based on such a model are in good agreement with the observed values. During calculations the role of the internal microenvironment upon the low-frequency motion is naturally revealed, so as to elucidate as well why this kind of low-frequency motion is so sensitive to the conformations of proteins observed.

PMID:
6362659
[PubMed - indexed for MEDLINE]
PMCID:
PMC1152424
Free PMC Article
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