Format

Send to:

Choose Destination
See comment in PubMed Commons below
Biochem Biophys Res Commun. 1983 Oct 14;116(1):86-90.

Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types.

Abstract

Ethylisopropyl-amiloride is 100 times more potent than amiloride for inhibiting the Na+/H+ exchanger of 3T3 fibroblasts, chick skeletal muscle cells and chick cardiac cells. Half-maximum effects, measured at 3 mM external Na+ are observed at 20-100 nM and 5 microM for ethylisopropyl-amiloride and amiloride respectively. As previously observed for amiloride, the effect of ethylisopropyl-amiloride is antagonized by external Na+ ions.

PMID:
6315011
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk