A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors

J Theor Biol. 1982 Jan 21;94(2):421-55. doi: 10.1016/0022-5193(82)90320-4.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Cations, Divalent
  • Iron / pharmacology
  • Ketoglutaric Acids / pharmacology
  • Kinetics
  • Macromolecular Substances
  • Malonates / pharmacology
  • Mathematics
  • Procollagen-Proline Dioxygenase / antagonists & inhibitors*
  • Protein Binding

Substances

  • Cations, Divalent
  • Ketoglutaric Acids
  • Macromolecular Substances
  • Malonates
  • Iron
  • Procollagen-Proline Dioxygenase