An epidemiological and clinical investigation upon ten cases of acute viral neuraxitis observed in the country of Alessandria between January 1978 - January 1979, is reported. Four cases of neuraxitis were due to coxsackie B4 virus, two to coxsackie B3, two to influenza type A and one to influenza type B virus, one to rubella and one to varicella-zooster virus. In all the cases blood chemistry, clinical and instrumental examinations (EEgraphy, cerebral scintigraphy and angiography) were coupled with determination of serum levels of complement fixing, haemagglutination inhibiting and neutralizing antibodies on two successive specimens, isolation of virus from cerebrospinal fluid, faeces and pharingeal secretions. Some particularly interesting epidemiological, immunological and clinical features of these neuraxitis are more fully discussed.