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Eur J Pediatr. 1980 Jun;134(1):69-74.

Achondrogenesis type I: light and electron-microscopic studies.

Abstract

The light- and electron-microscopic structure of articular and costal cartilage in a case of achondrogenesis type I has been described. The most characteristic ultrastructural change in the chondrocytes was conspicuous dilatation of the rough endoplasmatic reticulum (RER) which contained amorphous electronopaque material. This change in the RER was accompanied by marked hypertrophy of the Golgi apparatus; the matrix was basically unchanged.

PMID:
6250850
[PubMed - indexed for MEDLINE]
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