J Immunol. 1980 Jul;125(1):190-3.

Ecto-5'-nucleotidase activity in lymphoblastoid cell lines derived from heterozygotes for congenital X-linked agammaglobulinemia.

Thompson LF, Boss GR, Spiegelberg HL, Bianchino A, Seegmiller JE.

Abstract

Lymphoblastoid cell lines were established from female relatives of patients with congenital X-linked-agammaglobulinemia by Epstein-Barr virus transformation of their peripheral B lymphocytes. Cell lines derived from presumed carriers were characterized by low ecto-5'-nucleotidase activity and a reduced percentage of surface immunoglobulin-bearing cells. Measurement of ecto-5'-nucleotidase activity in newly established lymphoblastoid cell lines may provide a means for the identification of heterozygotes for congenital X-linked agammaglobulinemia.

PMID:: 6247393; [PubMed - indexed for MEDLINE]

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Ecto-5'-nucleotidase activities in lymphocytes and B lymphoblastoid cell lines from patients with congenital agammaglobulinemia. [Tohoku J Exp Med. 1983]
Ecto-5'-nucleotidase activities in lymphocytes and B lymphoblastoid cell lines from patients with congenital agammaglobulinemia.
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Webster AD, Rowe M, Johnson SM, Asherson GL, Harkness A. Ciba Found Symp. 1978; (68):135-51.
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Review Congenital agammaglobulinemia: a review.
Campbell JG, Riley HD Jr. South Med J. 1966 Nov; 59(11):1369-75.

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Cited by 1 PubMed Central article

Ecto-5'-nucleotidase activity in human T cell subsets. Decreased numbers of ecto-5'-nucleotidase positive cells from both OKT4+ and OKT8+ cells in patients with hypogammaglobulinemia. [J Clin Invest. 1983]
Ecto-5'-nucleotidase activity in human T cell subsets. Decreased numbers of ecto-5'-nucleotidase positive cells from both OKT4+ and OKT8+ cells in patients with hypogammaglobulinemia.
Thompson LF, Saxon A, O'Connor RD, Fox RI. J Clin Invest. 1983 Apr; 71(4):892-9.

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