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J Clin Microbiol. 1980 Jan;11(1):73-5.

Variable susceptibility of mice to group B coxsackievirus infections.

Abstract

Laboratory strains of group B coxsackievirus serotypes 1 to 6 were inoculated intraperitoneally into newborn mice of differing genetic backgrouns. Of the four genetic strains investigated, C3H mice appeared to be resistant to all six serotypes, whereas BALB/c mice were most susceptible. Swiss mice and a random-bred Swiss strain (COH) were intermediate in susceptibility. The findings underscore the fact that clinical isolation attempts and experimental studies involving group B coxsackieviruses must take into account both the virus strain used and the genetic background of the host. For clinical isolation of these viruses, the BALB/c mouse may be the most suitable of th strains tested.

PMID:
6243673
[PubMed - indexed for MEDLINE]
PMCID:
PMC273319
Free PMC Article
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