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Philos Trans R Soc Lond B Biol Sci. 1982 Sep 24;299(1094):3-6.

From interference to interferon: a brief historical introduction.


The idea that a substance mediating interference was released from cells upon contact with inactivated influenza A virus emerged from an abortive attempt at showing that interference was initiated by passage of only part of the virus into the cell, from previous knowledge about interference, and from the use of a simple technique allowing easy separation of fluid and tissue.

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