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J Rheumatol. 1982 Jul-Aug;9(4):603-6.

Studies of antinuclear antibodies in rheumatoid arthritis.

Abstract

Antinuclear antibodies (ANA) by the indirect immunofluorescence method and their immunospecificities were investigated in 60 patients with rheumatoid arthritis using HEp-2 cells as substrates. ANA were detected in 35% of the patients. The patterns of nuclear staining observed included: diffuse or patchy homogeneous (20%), speckled (8.3%), centromere (3.3%), nucleolar (1.6%) and in 1 patient a mixed pattern (1.6%). The presence of antihistone antibodies (20%) correlated with the presence of an homogeneous pattern on the HEp-2 cells.

PMID:
6182293
[PubMed - indexed for MEDLINE]
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