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Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control.
Power spectrum analysis of heart rate fluctuations provides a quantitative noninvasive means of assessing the functioning of the short-term cardiovascular control systems. We show that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz. Our data therefore provide evidence that the renin-angiotensin system plays a significant role in short-term cardiovascular control in the time scale of seconds to minutes.
PMID: 6166045 [PubMed - indexed for MEDLINE]
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Cited by 60 PubMed Central articles
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Measuring variability.
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[Ther Clin Risk Manag. 2008]
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[PLoS One. 2009]
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