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    Nucleic Acids Res. 1981 Feb 11;9(3):731-41.

    Bacterial synthesis of a novel human leukocyte interferon.

    Yelverton E, Leung D, Weck P, Gray PW, Goeddel DV.

    A novel human leukocyte interferon cDNA clone (LeIF B) was identified in a cDNA library prepared using polyadenylated mRNA of a myeloblastoid cell line. The nucleotide sequence of LeIF B differs significantly from other published leukocyte interferon cDNA sequences. An expression plasmid was constructed which directs the synthesis in E. coli of 8 x 10(7) interferon units per liter of culture. LeIF B exhibits markedly different specificities from another bacterially synthesized human leukocyte interferon, LeIF A.

    PMID: 6164048 [PubMed - indexed for MEDLINE]

    PMCID: 327233

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