The structure of one of the eight or more distinct...[Nature. 1980]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Nature. 1980 Oct 2;287(5781):401-8.Links

The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha.

Nagata S, Mantei N, Weissmann C.

The 12 interferon (IFN)-related sequences detected in a human gene bank fall into not less than eight distinct classes, indicating that there are at least eight IFN-related genes. Most, if not all, of these direct the synthesis of an IFN in Escherichia coli. The sequence of one chromosomal gene and its flanking regions was identical to that deduced for the cDNA corresponding to IFN-alpha l mRNA. No evidence was found for the existence of an intron, in either the coding or the non-coding segments of the gene.

PMID: 6159536 [PubMed - indexed for MEDLINE]

Evidence for a unique human fibroblast interferon (IFN-beta 1) chromosomal gene, devoid of intervening sequences.
Nucleic Acids Res. 1981 Feb 11; 9(3):461-71.

[Nucleic Acids Res. 1981]
Structure of the human immune interferon gene.
Nature. 1982 Aug 26; 298(5877):859-63.

[Nature. 1982]
DNA sequence of a major human leukocyte interferon gene.
Proc Natl Acad Sci U S A. 1981 Sep; 78(9):5435-9.

[Proc Natl Acad Sci U S A. 1981]
ReviewIsolation and characterization of a human fibroblast interferon gene and its expression in Escherichia coli.
Rev Infect Dis. 1981 Nov-Dec; 3(6):1186-95.

[Rev Infect Dis. 1981]
ReviewNucleotide sequence of the bovine growth hormone chromosomal gene.
Mol Cell Endocrinol. 1983 Nov; 33(1):81-95.

[Mol Cell Endocrinol. 1983]
» See reviews... | » See all...

Cited by 91 PubMed Central articles

Antiviral responses of human Leydig cells to mumps virus infection or poly I:C stimulation.
Le Tortorec A, Denis H, Satie AP, Patard JJ, Ruffault A, Jégou B, Dejucq-Rainsford N. Hum Reprod. 2008 Sep; 23(9):2095-103. Epub 2008 Jun 20.

[Hum Reprod. 2008]
Structure of a chromosomal gene for human interferon beta.
Ohno S, Taniguchi T. Proc Natl Acad Sci U S A. 1981 Sep; 78(9):5305-5309.

[Proc Natl Acad Sci U S A. 1981]
Pre-mRNA processing enhancer (PPE) elements from intronless genes play additional roles in mRNA biogenesis than do ones from intron-containing genes.
Guang S, Mertz JE. Nucleic Acids Res. 2005; 33(7):2215-26. Epub 2005 Apr 20.

[Nucleic Acids Res. 2005]
» See all...

Patient Drug Information

Glatiramer Acetate (Copaxone, Avonex, Rebif, ...)
How effective are disease-modifying drugs in the treatment of multiple sclerosis?
Source: AHFS Consumer Medication Information

Recent Activity

Clear Turn Off Turn On

The structure of one of the eight or more distinct chromosomal genes for human interferon-...The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha.

Related articles

Cited by 91 PubMed Central articles

Patient Drug Information

Recent Activity