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Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration.
Biopsy specimens were taken from intact areas of antral mucosa in 100 consecutive consenting patients presenting for gastroscopy. Spiral or curved bacilli were demonstrated in specimens from 58 patients. Bacilli cultured from 11 of these biopsies were gram-negative, flagellate, and microaerophilic and appeared to be a new species related to the genus Campylobacter. The bacteria were present in almost all patients with active chronic gastritis, duodenal ulcer, or gastric ulcer and thus may be an important factor in the aetiology of these diseases.
PMID: 6145023 [PubMed - indexed for MEDLINE]
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Cited by over 100 PubMed Central articles
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Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization.
Chen J, Zhang L, Zhang Y, Zhang H, Du J, Ding J, Guo Y, Jiang H, Shen X.
BMC Microbiol. 2009 May 12; 9:91. Epub 2009 May 12.
[BMC Microbiol. 2009]
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Frequency of vacA, cagA and babA2 virulence markers in Helicobacter pylori strains isolated from Mexican patients with chronic gastritis.
Paniagua GL, Monroy E, Rodríguez R, Arroniz S, Rodríguez C, Cortés JL, Camacho A, Negrete E, Vaca S.
Ann Clin Microbiol Antimicrob. 2009 Apr 30; 8:14. Epub 2009 Apr 30.
[Ann Clin Microbiol Antimicrob. 2009]
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ReviewWhere are all the Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease?
Pierce ES.
PLoS Pathog. 2009 Mar; 5(3):e1000234. Epub 2009 Mar 27.
[PLoS Pathog. 2009]
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