Abstract
12 patients with troublesome hot flushes after orchidectomy (as a primary treatment for prostatic carcinoma) were treated with cyproterone acetate or placebo in a double-blind cross-over trial. The frequency of hot flushes was significantly reduced during the three weeks that cyproterone acetate (100 mg three times a day) was given. 5 patients complained of lassitude while on cyproterone acetate, but in none was it necessary to discontinue treatment.
Publication types
-
Clinical Trial
-
Randomized Controlled Trial
MeSH terms
-
Aged
-
Androgen Antagonists / therapeutic use*
-
Castration / adverse effects*
-
Climacteric / drug effects*
-
Clinical Trials as Topic
-
Cyproterone / analogs & derivatives*
-
Cyproterone / therapeutic use
-
Cyproterone Acetate
-
Double-Blind Method
-
Flushing / drug therapy*
-
Humans
-
Male
-
Middle Aged
-
Prostatic Neoplasms / therapy
-
Random Allocation
Substances
-
Androgen Antagonists
-
Cyproterone Acetate
-
Cyproterone