Int J Gynaecol Obstet. 1980;18(4):275-9.

Quinacrine hydrochloride pellets: preliminary data on a nonsurgical method of female sterilization.

Zipper J, Cole LP, Goldsmith A, Wheeler R, Rivera M.

Abstract

The efficacy of transcervical insertions of quinacrine hydrochloride pellets to produce tubal occlusion has been evaluated in a study of 139 women in Santiago, Chile. At one year, the pregnancy rate was 3.1%, an acceptable rate for a nonsurgical method of female sterilization.

PIP:

139 volunteers seeking permanent sterilization were treated with 3 transcervical insertions of quinacrine hydrochloride pellets to produce tubal occlusion. The procedure is essentially the same as inserting an IUD. Pregnancy rate at 1 year was 3.1%, and results showed this method to be more effective than the quinacrine solution method, which entails a higher risk of transient toxic psychosis.

PMID:: 6109672; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH Terms

Substances

Quinacrine

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Tubal Ligation - MedlinePlus Health Information

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QUINACRINE - HSDB

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Related citations in PubMed

Efficacy of two insertions of 100-minute releasing quinacrine hydrochloride pellets for non-surgical female sterilization. [Adv Contracept. 1987]
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