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Lancet. 1980 Feb 16;1(8164):339-40.

Possible prevention of neural-tube defects by periconceptional vitamin supplementation.

Abstract

Women who had previously given birth to one or more infants with a neural-tube defect (NTD) were recruited into a trial of periconceptional multivitamin supplementation. 1 of 178 infants/fetuses of fully supplemented mothers (0.6%) had an NTD, compared with 13 of 260 infants/fetuses of unsupplemented mothers (5.0%).

PMID:
6101792
[PubMed - indexed for MEDLINE]
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