Abstract
The base sequence of large part of the mitochondrial DNA of Wistar rats is presented. The sequence is compared with those of other mammalian mitochondrial DNAs. The nucleotide and amino acid homologies, codon strategy, nature and patterns of substitutions are reported. It results a very high amount of silent substitutions and, in short divergence time, a predominance of transitions on transversions. In both types of substitutions a strong bias in avoiding the use of the G in the third codon position is observed.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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ATP Synthetase Complexes
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Amino Acid Sequence
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Animals
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Base Sequence
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Cattle
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Codon*
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DNA, Mitochondrial*
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Electron Transport Complex IV / genetics*
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Humans
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Mice
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Multienzyme Complexes / genetics*
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Phosphotransferases / genetics*
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RNA, Messenger*
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Rats
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Rats, Inbred Strains
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Species Specificity
Substances
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Codon
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DNA, Mitochondrial
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Multienzyme Complexes
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RNA, Messenger
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Electron Transport Complex IV
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Phosphotransferases
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ATP Synthetase Complexes