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Nature. 1984 Oct 18-24;311(5987):626-31.

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.

Abstract

We have purified the human T-cell growth factor (interleukin-2) receptor and have cloned, sequenced and expressed cDNAs corresponding to this receptor. We identify one gene, but two interleukin-2 receptor mRNAs which differ in their polyadenylation signals. We have isolated an additional cDNA that may correspond to an alternatively spliced mRNA that lacks a 216 base segment and appears to encode an altered membrane protein which cannot bind interleukin-2.

PMID:
6090948
[PubMed - indexed for MEDLINE]
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