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Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization.
The isolation of a cDNA clone containing the complete coding region for human purine nucleoside phosphorylase (PNP) has been described previously. In this report we present the nucleotide sequence of this cDNA clone and compare the derived amino acid sequence, encoding a protein of 32 kilodaltons, with the published amino acid composition. Using a fragment of the cDNA clone as a probe, human PNP genomic clones from a bacteriophage lambda library have been isolated and the structural organization of the wild type PNP gene determined.
PMID: 6087295 [PubMed - indexed for MEDLINE]
PMCID: PMC320030
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Cited by 12 PubMed Central articles
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YLR209c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase.
Lecoq K, Belloc I, Desgranges C, Konrad M, Daignan-Fornier B.
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[J Bacteriol. 2001]
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Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli.
Seeger C, Poulsen C, Dandanell G.
J Bacteriol. 1995 Oct; 177(19):5506-16.
[J Bacteriol. 1995]
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Expression of a cDNA sequence encoding human purine nucleoside phosphorylase in rodent and human cells.
McIvor RS, Goddard JM, Simonsen CC, Martin DW Jr.
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[Mol Cell Biol. 1985]
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