J Nucl Med. 1977 Dec;18(12):1159-66.

The radionuclide ejection fraction: a comparison of three radionuclide techniques with contrast angiography.

Folland ED, Hamilton GW, Larson SM, Kennedy JW, Williams DL, Ritchie JL.

Abstract

Left-ventricular ejection fraction (EF) can be measured by several radionuclide methods. The EFs determined by three such methods (first-transit time-activity, equilibrium blood-pool time-activity, and equilibrium blood-pool area-length) were compared in 30 patients with EFs measured by area-length analysis of x-ray contrast angiograms. Both time-activity methods (first-transit and blood-pool) yielded EFs that correlated well with x-ray contrast EFs (r=0.86 and 0.84, respectively). Area-length analysis of blood-pool images yielded EFs that agreed less well with x-ray contrast EFs (r=0.73 in the RAO view, 0.70 in the LAO view). We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.

PMID:: 606737; [PubMed - indexed for MEDLINE]

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