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Visual pathway mediating pineal response to environmental light.
Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light. Response to environmental light is initiated in the retina and transmitted to the pineal by way of the central nervous system and the cervical sympathetics. The central visual pathway essential for mediation of this response is the inferior accessory optic tract. Visual pathways to thalamus and tectum do not participate in this response.
PMID: 6015532 [PubMed - indexed for MEDLINE]
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Cited by 5 PubMed Central articles
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History of the development of sleep medicine in the United States.
Shepard JW Jr, Buysse DJ, Chesson AL Jr, Dement WC, Goldberg R, Guilleminault C, Harris CD, Iber C, Mignot E, Mitler MM, et al.
J Clin Sleep Med. 2005 Jan 15; 1(1):61-82.
[J Clin Sleep Med. 2005]
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Extraretinal light perception in the sparrow. II. Photoperiodic stimulation of testis growth.
Menaker M, Keatts H.
Proc Natl Acad Sci U S A. 1968 May; 60(1):146-51.
[Proc Natl Acad Sci U S A. 1968]
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The ultrastructure of the pineal ganglion in the ferret.
David GF, Herbert J, Wright GD.
J Anat. 1973 May; 115(Pt 1):79-97.
[J Anat. 1973]
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