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Br Med J. 1969 Sep 6;3(5670):564-7.

Severe depressive mood changes following slow-release intramuscular fluphenazine injection.

Abstract

Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection. In five cases this depression is thought to have been responsible for suicide. In 8 out of 10 cases the depression responded to electroplexy (E.C.T.). It is recommended that patients who are treated with fluphenazine should be carefully supervised.

PMID:
5808010
[PubMed - indexed for MEDLINE]
PMCID:
PMC1984352
Free PMC Article
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