Pharmacol Biochem Behav. 1978 May;8(5):509-14.

Glutamic acid and ethanol dependence.

Abstract

Glutamate diethyl ester, a specific glutamate antagonist, attenuated the seizures and decreases in behavioral activity that were observed in mice during withdrawal. Prior to withdrawal, ethanol-dependent animals were supersensitive to kainic acid, a potent glutamate agonist, but they were not supersensitive to the convulsant drug pentylenetetrazol. These findings suggest that supersensitivity to glutamate develops during ethanol dependence, and that this phenomenon contributes to the signs of ethanol withdrawl.

PMID:: 566932; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Medical

Alcoholism - MedlinePlus Health Information

Molecular Biology Databases

ETHANOL - HSDB

Supplemental Content

Save items

Related citations in PubMed

Repeated ethanol withdrawal experience selectively alters sensitivity to different chemoconvulsant drugs in mice. [Psychopharmacology (Berl). 1998]
Repeated ethanol withdrawal experience selectively alters sensitivity to different chemoconvulsant drugs in mice.
Becker HC, Veatch LM, Diaz-Granados JL. Psychopharmacology (Berl). 1998 Sep; 139(1-2):145-53.
Brain catecholamines and ethanol: involvement in physical dependence and withdrawal. [Adv Exp Med Biol. 1977]
Brain catecholamines and ethanol: involvement in physical dependence and withdrawal.
Pohorecky LA. Adv Exp Med Biol. 1977; 85A:495-513.
Mapping rat brain structures activated during ethanol withdrawal: role of glutamate and NMDA receptors. [Eur J Pharmacol. 1992]
Mapping rat brain structures activated during ethanol withdrawal: role of glutamate and NMDA receptors.
Morgan PF, Nadi NS, Karanian J, Linnoila M. Eur J Pharmacol. 1992 Mar 12; 225(3):217-23.
Review Alcohol withdrawal seizures: implications of kindling. [Pharmacol Biochem Behav. 1980]
Review Alcohol withdrawal seizures: implications of kindling.
Pinel JP. Pharmacol Biochem Behav. 1980; 13 Suppl 1:225-31.
Review Comparison of cocaine- and methamphetamine-evoked dopamine and glutamate overflow in somatodendritic and terminal field regions of the rat brain during acute, chronic, and early withdrawal conditions. [Ann N Y Acad Sci. 2001]
Review Comparison of cocaine- and methamphetamine-evoked dopamine and glutamate overflow in somatodendritic and terminal field regions of the rat brain during acute, chronic, and early withdrawal conditions.
Zhang Y, Loonam TM, Noailles PA, Angulo JA. Ann N Y Acad Sci. 2001 Jun; 937:93-120.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Glutamic acid and ethanol dependence.
Glutamic acid and ethanol dependence.
Pharmacol Biochem Behav. 1978 May ;8(5):509-14.

PubMed
Metachromatic leukodystrophy: diagnosis with samples of venous blood.
Metachromatic leukodystrophy: diagnosis with samples of venous blood.
Science. 1968 Aug 9 ;161(3841):594-5.

PubMed
[Old and new dangers of blood transfusion (author's transl)].
[Old and new dangers of blood transfusion (author's transl)].
MMW Munch Med Wochenschr. 1976 May 28 ;118(22):713-8.

PubMed
[Methylation of 3'-terminal nucleotides of tRNA and its function].
[Methylation of 3'-terminal nucleotides of tRNA and its function].
Biokhimiia. 1968 Jan-Feb ;33(1):111-20.

PubMed
Anaerobic and aerobic urethral flora in healthy females.
Anaerobic and aerobic urethral flora in healthy females.
J Clin Microbiol. 1978 Jul ;8(1):67-72.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Glutamic acid and ethanol dependence.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information