Science. 1968 Aug 9;161(3841):594-5.

Metachromatic leukodystrophy: diagnosis with samples of venous blood.

Abstract

Arylsulfatase A and B have been demonstrated in preparations of human leukocytes. The level of activity of arylsulfatase A is markedly decreased in the preparations from patients with metachromatic leukodystrophy. Acid phosphatase and arylsulfatase B activities were normal. The assay of arylsulfatase A in leukocyte preparations can be useful in the diagnosis of metachromatic leukodystrophy while obviating the difficulties of current methods.

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[Diagnostic value of the determination of intraleukocytic arylsulfatase for the early detection of metachromatic leukodystrophy]. [Presse Med. 1971]
[Diagnostic value of the determination of intraleukocytic arylsulfatase for the early detection of metachromatic leukodystrophy].
Baumann N, Turpin JC, Castaigne P. Presse Med. 1971 Jan 30; 79(6):244-5.
Arylsulfatase A activity in human urine: quantitative studies on patients with lysosomal disorders including metachromatic leukodystrophy. [Clin Chim Acta. 1972]
Arylsulfatase A activity in human urine: quantitative studies on patients with lysosomal disorders including metachromatic leukodystrophy.
Thomas GH, Howell RR. Clin Chim Acta. 1972 Jan; 36(1):99-103.
An improved method for the determination of leukocyte arylsulfatase A and its application to the diagnosis of metachromatic leukodystrophy in homozygous and heterozygous states. [Clin Chim Acta. 1972]
An improved method for the determination of leukocyte arylsulfatase A and its application to the diagnosis of metachromatic leukodystrophy in homozygous and heterozygous states.
Potter JL, Timmons GD, Rinehart L, Witmer EJ. Clin Chim Acta. 1972 Jul; 39(2):518-23.
Review The use of white cells as a source of diagnostic material for lipid storage diseases. [Clin Chim Acta. 1969]
Review The use of white cells as a source of diagnostic material for lipid storage diseases.
Snyder RA, Brady RO. Clin Chim Acta. 1969 Aug; 25(2):331-8.
Review Prenatal genetic diagnosis (second of three parts). [N Engl J Med. 1970]
Review Prenatal genetic diagnosis (second of three parts).
Milunsky A, Littlefield JW, Kanfer JN, Kolodny EH, Shih VE, Atkins L. N Engl J Med. 1970 Dec 24; 283(26):1441-7.

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Cited by 14 PubMed Central articles

Enhancement of residual arylsulfatase B activity in feline mucopolysaccharidosis VI by thiol-induced subunit association. [J Clin Invest. 1982]
Enhancement of residual arylsulfatase B activity in feline mucopolysaccharidosis VI by thiol-induced subunit association.
Vine DT, McGovern MM, Schuchman EH, Haskins ME, Desnick RJ. J Clin Invest. 1982 Feb; 69(2):294-302.
Review Genetic heterogeneity in metachromatic leukodystrophy. [Am J Hum Genet. 1982]
Review Genetic heterogeneity in metachromatic leukodystrophy.
Kihara H. Am J Hum Genet. 1982 Mar; 34(2):171-81.
The genetics of the aryl sulfatase A locus. [Am J Hum Genet. 1981]
The genetics of the aryl sulfatase A locus.
Schaap T, Zlotogora J, Elian E, Barak Y, Bach G. Am J Hum Genet. 1981 Jul; 33(4):531-9.

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Metachromatic leukodystrophy: diagnosis with samples of venous blood.
Metachromatic leukodystrophy: diagnosis with samples of venous blood.
Science. 1968 Aug 9 ;161(3841):594-5.

PubMed
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Metachromatic leukodystrophy: diagnosis with samples of venous blood.

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