Postgrad Med J. 1979 Dec;55(654):868-9.

Axillary hyperhidrosis - topical treatment with aluminium chloride hexahydrate.

Abstract

Forty-two patients with axillary hyperhidrosis on the waiting list for surgery were treated with topical saturated solution of aluminium chloride hexahydrate in absolute alcohol. There have been 7 failures. Three patients were unable to cope with the treatment and 4 more experienced severe local irritation or soreness; these 4 were submitted to local surgery. This is a simple and effective treatment for the majority of cases of severe axillary sweating.

PMID:: 548949; [PubMed - indexed for MEDLINE]
PMCID:: PMC2425692

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Axillary hyperhidrosis treated with alcoholic solution of aluminium chloride hexahydrate. [Br Med J. 1978]
Axillary hyperhidrosis treated with alcoholic solution of aluminium chloride hexahydrate.
Scholes KT, Crow KD, Ellis JP, Harman RR, Saihan EM. Br Med J. 1978 Jul 8; 2(6130):84-5.
[Axillary hyperhydrosis. Local treatment with 25% aluminum chloride hexahydrate in absolute alcohol]. [Ugeskr Laeger. 1978]
[Axillary hyperhydrosis. Local treatment with 25% aluminum chloride hexahydrate in absolute alcohol].
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Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine. [Acta Derm Venereol. 1988]
Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine.
Glent-Madsen L, Dahl JC. Acta Derm Venereol. 1988; 68(1):87-9.
Review Current therapeutic strategies for hyperhidrosis: a review. [Eur J Dermatol. 2002]
Review Current therapeutic strategies for hyperhidrosis: a review.
Togel B, Greve B, Raulin C. Eur J Dermatol. 2002 May-Jun; 12(3):219-23.
Review Current treatments for axillary hyperhidrosis. [Surgeon. 2004]
Review Current treatments for axillary hyperhidrosis.
Fitzgerald E, Feeley TM, Tierney S. Surgeon. 2004 Dec; 2(6):311-4, 360.

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Cited by 5 PubMed Central articles

Aluminum chloride hexahydrate in a salicylic Acid gel: a novel topical agent for hyperhidrosis with decreased irritation. [J Clin Aesthet Dermatol. 2009]
Aluminum chloride hexahydrate in a salicylic Acid gel: a novel topical agent for hyperhidrosis with decreased irritation.
Woolery-Lloyd H, Valins W. J Clin Aesthet Dermatol. 2009 Jun; 2(6):28-31.
Review Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide. [J Toxicol Environ Health B Cri...]
Review Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide.
Krewski D, Yokel RA, Nieboer E, Borchelt D, Cohen J, Harry J, Kacew S, Lindsay J, Mahfouz AM, Rondeau V. J Toxicol Environ Health B Crit Rev. 2007; 10 Suppl 1:1-269.
Surgery of the sweat glands. [J R Soc Med. 1982]
Surgery of the sweat glands.
Ellis H. J R Soc Med. 1982 Aug; 75(8):585-7.

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