Br Med J. 1970 Nov 28;4(5734):525-7.

Effects of large doses of colistin sulphomethate sodium on renal function.

Abstract

High doses of colistin were used in the treatment of severely ill patients with refractory klebsiella chest and urinary tract infections. At the same time renal function was monitored to determine possible nephrotoxicity. In all patients it produced acute renal failure and in some acute tubular necrosis. Though renal failure contributed to the final cause of death in some cases, in the majority death was due to the primary neurological illness.

PMID:: 5483321; [PubMed - indexed for MEDLINE]
PMCID:: PMC1820005

Free PMC Article

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Intravenous colistin sulphomethate in acute respiratory exacerbations in adult patients with cystic fibrosis. [Thorax. 1997]
Intravenous colistin sulphomethate in acute respiratory exacerbations in adult patients with cystic fibrosis.
Conway SP, Pond MN, Watson A, Etherington C, Robey HL, Goldman MH. Thorax. 1997 Nov; 52(11):987-93.
Nephrotoxicity of intravenous colistin: a prospective evaluation. [Int J Antimicrob Agents. 2005]
Nephrotoxicity of intravenous colistin: a prospective evaluation.
Falagas ME, Fragoulis KN, Kasiakou SK, Sermaidis GJ, Michalopoulos A. Int J Antimicrob Agents. 2005 Dec; 26(6):504-7. Epub 2005 Nov 8.
Renal impairment in cystic fibrosis patients due to repeated intravenous aminoglycoside use. [Pediatr Pulmonol. 2005]
Renal impairment in cystic fibrosis patients due to repeated intravenous aminoglycoside use.
Al-Aloul M, Miller H, Alapati S, Stockton PA, Ledson MJ, Walshaw MJ. Pediatr Pulmonol. 2005 Jan; 39(1):15-20.
Intravenous colistin sulphomethate sodium for therapy of infections due to multidrug-resistant gram-negative bacteria. [J Infect. 2008]
Intravenous colistin sulphomethate sodium for therapy of infections due to multidrug-resistant gram-negative bacteria.
Pintado V, San Miguel LG, Grill F, Mejía B, Cobo J, Fortún J, Martín-Dávila P, Moreno S. J Infect. 2008 Mar; 56(3):185-90. Epub 2008 Feb 15.
Review Acute renal failure due to ciprofloxacin. [Arch Intern Med. 1990]
Review Acute renal failure due to ciprofloxacin.
Allon M, Lopez EJ, Min KW. Arch Intern Med. 1990 Oct; 150(10):2187-9.

See reviews... See all...

Cited by 7 PubMed Central articles

Safety and efficacy of polymyxin B in multidrug resistant Gram-negative severe sepsis and septic shock. [Indian J Crit Care Med. 2008]
Safety and efficacy of polymyxin B in multidrug resistant Gram-negative severe sepsis and septic shock.
Ramasubban S, Majumdar A, Das PS. Indian J Crit Care Med. 2008 Oct; 12(4):153-7.
Review Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. [Crit Care. 2006]
Review Toxicity of polymyxins: a systematic review of the evidence from old and recent studies.
Falagas ME, Kasiakou SK. Crit Care. 2006 Feb; 10(1):R27.
Toxicity after prolonged (more than four weeks) administration of intravenous colistin. [BMC Infect Dis. 2005]
Toxicity after prolonged (more than four weeks) administration of intravenous colistin.
Falagas ME, Rizos M, Bliziotis IA, Rellos K, Kasiakou SK, Michalopoulos A. BMC Infect Dis. 2005 Jan 10; 5:1. Epub 2005 Jan 10.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Effects of large doses of colistin sulphomethate sodium on renal function.
Effects of large doses of colistin sulphomethate sodium on renal function.
Br Med J. 1970 Nov 28 ;4(5734):525-7.

PubMed
Cystic fibrosis in adults: an autopsy study.
Cystic fibrosis in adults: an autopsy study.
Pathol Annu. 1979 ;14 Pt 2:357-82.

PubMed
547223[uid] (1)
PubMed
Adverse effects of sodium colistimethate. Manifestations and specific reaction r...
Adverse effects of sodium colistimethate. Manifestations and specific reaction rates during 317 courses of therapy.
Ann Intern Med. 1970 Jun ;72(6):857-68.

PubMed
The clinical spectrum of ankylosing spondylitis.
The clinical spectrum of ankylosing spondylitis.
Clin Orthop Relat Res. 1979 Sep ;(143):53-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Effects of large doses of colistin sulphomethate sodium on renal function.

Abstract

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 7 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information