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Science. 1970 Feb 6;167(3919):871-3.

Cystic fibrosis: characterization of the inhibitor to ciliary action in oyster gills.

Abstract

The inhibitor to oyster ciliary activity was isolated from serumof cystic fibrosis patients and heterozygotes. The inhibitinig protein fraction wast a cation as judged by electrophoresis; it had a molecuer weight of 125,000 to 200,000 as judged by gel filtration; antd oil diethylaminoethyl-cellulose chromatography it eluted with the immunoglobulin G fraction. The analogous fraction in normal individuals did not inhibit oyster cillary activity.

PMID:
5410849
[PubMed - indexed for MEDLINE]
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