Ukr Biokhim Zh. 1979 Sep-Oct;51(5):474-6.

[Contents of putrescine, spermidine and spermine in tissue of the human brain glial tumors].

[Article in Russian]

Abstract

It is shown that in the tissue of the human brain glial tumours the content of putrescine depends on the degree of the tumour malignization. In malignant gliomas (glioblastomas), as compared to the benign (astrocytomas), the content of putrescine is significantly higher. The content of spermidine in glial tumours of a malignancy different degree is twice as high as the level of this polyamine in the brain grey matter, and it is twice as low as in the white matter. The content of spermine in the brain glial tumours does not differ essentially from its level in the brain tissue.

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