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Nature. 1975 Aug 7;256(5517):471-3.

Integration of viral genomes.

Abstract

DNA transcripts of infectious RNA viruses were found to be integrated in the DNA of chronically-infected tissue cultures. DNA sequences homologous to RNA of measles virus were found in tissues affected with systemic lupus erythemotosus. These data open up a new class of virus-cell interaction that may be a result of cooperation between infectious and oncogenic viruses.

PMID:
51475
[PubMed - indexed for MEDLINE]
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