Abstract
Avermectin B1a given at a dose level of 0.05 or 0.1 mg/kg of body weight caused rapid removal of Dirofilaria immitis microfilariae from the blood of dogs with heartworm infections. If the adult worms were also killed with an arsenical (melarsoprol), the removal of microfilariae was permanent.
MeSH terms
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Animals
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Anthelmintics / therapeutic use*
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Blood / parasitology
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Dirofilariasis / drug therapy
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Dirofilariasis / parasitology
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Dirofilariasis / veterinary*
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Disaccharides / therapeutic use
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Dog Diseases / drug therapy*
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Dog Diseases / parasitology
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Dogs
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Ivermectin / analogs & derivatives
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Lactones / therapeutic use*
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Microfilariae
Substances
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Anthelmintics
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Disaccharides
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Lactones
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Ivermectin
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avermectin