Biochem J. 1972 Mar;127(1):1-10.

The deoxyribonucleic acid modification enzyme of bacteriophage P1.

Abstract

The bacteriophage P1 modification enzyme, assayed by the specific methylation of unmodified bacteriophage 82 DNA, has been purified 500-fold from a bacteriophage P1 lysogen of Escherichia coli. The enzyme catalyses the incorporation of approximately 20-24 methyl groups per bacteriophage 82 DNA molecule. The sole product of methylation is 6-methylaminopurine. Methylation of unmodified bacteriophage DNA confers protection against a challenge by purified bacteriophage P1 restriction enzyme. The pH optimum is 6.0-6.25: the apparent K(m) for S-adenosyl-l-methionine is 5x10(-6)m.

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The deoxyribonucleic acid-modification enzyme of bacteriophage P1. Subunit structure. [Biochem J. 1973]
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The deoxyribonucleic acid modification enzyme of bacteriophage P1.
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The deoxyribonucleic acid modification enzyme of bacteriophage P1.

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