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Science. 1972 Sep 29;177(4055):1205-7.

Human prolactin: 24-hour pattern with increased release during sleep.

Abstract

Human prolactin was measured in plasma by radioimmunoassay at 20 minute intervals for a 24-hour period in each of six normal adults, whose sleep-wake cycles were monitored polygraphically. A marked diurnal variation in plasma concentrations was demonstrated, with highest values during sleep; periods of episodic release occurred throughout the 24 hours.

PMID:
5057627
[PubMed - indexed for MEDLINE]
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