Nahrung. 1979;23(6):611-20.

[Acute and subchronic experiments on the effects of microcrystalline cellulose on various pharmacological and biochemical parameters in mongrel rabbits].

[Article in German]

Möritz KU, Grisk A, Schröder LW, Siegmund W, Hegewald G, Königstedt B, Ehrlers D, Graf W, Riemer F, Bärenwald G, Bercher H, Fermum R.

Abstract

The subchronic intravenous application of microcrystalline cellulose (MCC), in a dose of 5 mg/kg twice weekly for 10 weeks, resulted in servere crystal embolism in the lungs of the animals. The clinical parameters were either unchanged (erythrocyte and leucocyte counts, differential blood picture, osmotic resistance of the erythrocytes, total serum bilirubin, serum protein and serum protein fractions) or slightly pathological (hemoglobin content, hematocrit, GOT and GPT). The results from tests of the liver function (by means of bromosulphthaleine clearance) and of the renal function as well as the ophthalmologic examination were not indicative of damaged parenchyma or disturbed microcirculation. Intra-arterial infusions of MCC affected the peripheral muscular blood supply, blood pressure and heart rate.

PMID:: 503180; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

English Abstract

MeSH Terms

Substances

Supplemental Content

Related citations

Subchronic intravenous toxicity studies with gamma-cyclodextrin in rats. [Regul Toxicol Pharmacol. 1998]
Subchronic intravenous toxicity studies with gamma-cyclodextrin in rats.
Donaubauer HH, Fuchs H, Langer KH, Bär A. Regul Toxicol Pharmacol. 1998 Apr; 27(2):189-98.
NTP Toxicology and Carcinogenesis Studies of 4,4'-Thiobis(6- t -butyl- m -cresol) (CAS No. 96-69-5) in F344/N Rats and B6C3F1 Mice (Feed Studies). [Natl Toxicol Program Tech Rep Ser. 1994]
NTP Toxicology and Carcinogenesis Studies of 4,4'-Thiobis(6- t -butyl- m -cresol) (CAS No. 96-69-5) in F344/N Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 1994 Dec; 435:1-288.
NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies). [Natl Toxicol Program Tech Rep Ser. 1993]
NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 1993 Sep; 422:1-340.
Prevention of biochemical changes in gamma-irradiated rats by some metal complexes. [Clin Chem Lab Med. 2003]
Prevention of biochemical changes in gamma-irradiated rats by some metal complexes.
Abou-Seif MA, El-Naggar MM, El-Far M, Ramadan M, Salah N. Clin Chem Lab Med. 2003 Jul; 41(7):926-33.
Review Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin. [Int J Toxicol. 2007]
Review Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
. Int J Toxicol. 2007; 26 Suppl 1:3-106.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

[Acute and subchronic experiments on the effects of microcrystalline cellulose o...
[Acute and subchronic experiments on the effects of microcrystalline cellulose on various pharmacological and biochemical parameters in mongrel rabbits].
Nahrung. 1979 ;23(6):611-20.

PubMed
Cluster of testicular cancer in police officers exposed to hand-held radar.
Cluster of testicular cancer in police officers exposed to hand-held radar.
Am J Ind Med. 1993 Aug ;24(2):231-3.

PubMed
The signing brain: the neurobiology of sign language.
The signing brain: the neurobiology of sign language.
Trends Cogn Sci. 2008 Nov ;12(11):432-40.

PubMed
Sebaceous gland lipids
Sebaceous gland lipids
Dermatoendocrinol. 2009; 1(2): 68-71.

PMC
Sphingosine-1-phosphate signaling and the skin.
Sphingosine-1-phosphate signaling and the skin.
Am J Clin Dermatol. 2007 ;8(6):329-36.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

[Acute and subchronic experiments on the effects of microcrystalline cellulose on various pharmacological and biochemical parameters in mongrel rabbits].

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Supplemental Content

Related citations

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information