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Evaluation of methods for estimating the dissociation constant of tight binding enzyme inhibitors.
PMID: 500698 [PubMed - indexed for MEDLINE]
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Cited by 8 PubMed Central articles
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Slow-tight-binding inhibition of enoyl-acyl carrier protein reductase from Plasmodium falciparum by triclosan.
Kapoor M, Reddy CC, Krishnasastry MV, Surolia N, Surolia A.
Biochem J. 2004 Aug 1; 381(Pt 3):719-24.
[Biochem J. 2004]
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ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease.
Sham HL, Kempf DJ, Molla A, Marsh KC, Kumar GN, Chen CM, Kati W, Stewart K, Lal R, Hsu A, et al.
Antimicrob Agents Chemother. 1998 Dec; 42(12):3218-24.
[Antimicrob Agents Chemother. 1998]
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The kinetics of slow-binding and slow, tight-binding inhibition: the effects of substrate depletion.
Waley SG.
Biochem J. 1993 Aug 15; 294 ( Pt 1):195-200.
[Biochem J. 1993]
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Patient Drug Information
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Folic Acid (Folvite® )
Folic acid is used to treat or prevent folic acid deficiency. It is a B-complex vitamin needed by the body to manufacture red blood cells. A deficiency of this vitamin causes certain types of anemia (low red blood cell c...
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Methotrexate (Rheumatrex® , Trexall® )
Methotrexate is used to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) that cannot be controlled by other treatments. Methotrexate is also used along with rest, physica...