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Mutat Res. 1979 Aug;62(1):183-90.

A seventh complementation group in excision-deficient xeroderma pigmentosum.

Abstract

Cells from a xeroderma pigmentosum patient XP2BI who has reached 17 years of age with no keratoses or skin tumours constitute a new, 7th complementation group G. These cells exhibit a low residual level of excision repair, 2% of normal after a UV dose of 5 J/m2 and an impairment of post-replication repair characteristic of excision-defective XPs. They are also sensitive to the lethal effects of UV and defective in host-cell reactivation of UV-irradiated SV40 DNA.

PMID:
492197
[PubMed - indexed for MEDLINE]
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