Science. 1974 Aug 9;185(4150):529-31.

Free radicals and inflammation: protection of synovial fluid by superoxide dismutase.

Abstract

Enzymatically genierated superoxide radical. by reactitng with hydrogen peroxide to prduce the hydroxyl radical, depolymerized puirified hyaluronic acid and bovine synovial flulid. Since phagocytizing polymorphonuclear leukocytes produce superoxide radicals, this reac-tion is sutggested and shown to be quantitatively feasible as the ini vivo mechanism of synovial fluid degradation in anl inflamed joint. Superoxide dismutase, and catalase protect synaovial fluid against such degradation in vitro.

PMID:: 4841157; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Joint Disorders - MedlinePlus Health Information

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Protection against superoxide and hydrogen peroxide in synovial fluid from rheumatoid patients. [Clin Sci (Lond). 1981]
Protection against superoxide and hydrogen peroxide in synovial fluid from rheumatoid patients.
Blake DR, Hall ND, Treby DA, Halliwell B, Gutteridge JM. Clin Sci (Lond). 1981 Oct; 61(4):483-6.
Effect of palosein (superoxide dismutase) and catalase upon oxygen derived free radical induced degradation of equine synovial fluid. [Equine Vet J. 1990]
Effect of palosein (superoxide dismutase) and catalase upon oxygen derived free radical induced degradation of equine synovial fluid.
Auer DE, Ng JC, Seawright AA. Equine Vet J. 1990 Jan; 22(1):13-7.
Protective factors against oxygen free radicals and hydrogen peroxide in rheumatoid arthritis synovial fluid. [Arthritis Rheum. 1984]
Protective factors against oxygen free radicals and hydrogen peroxide in rheumatoid arthritis synovial fluid.
Biemond P, Swaak AJ, Koster JF. Arthritis Rheum. 1984 Jul; 27(7):760-5.
Review Oxygen free radicals and corneal endothelium. [Lens Eye Toxic Res. 1989]
Review Oxygen free radicals and corneal endothelium.
Hull DS, Green K. Lens Eye Toxic Res. 1989; 6(1-2):87-91.
Review Defence against the toxic action of oxygen. [Sb Ved Pr Lek Fak Karlovy Univ...]
Review Defence against the toxic action of oxygen.
Stoklasová A. Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1989; 32(1):157-68.

See reviews... See all...

Cited by 88 PubMed Central articles

Protective effects of manganese(II) chloride on hyaluronan degradation by oxidative system ascorbate plus cupric chloride. [Interdiscip Toxicol. 2010]
Protective effects of manganese(II) chloride on hyaluronan degradation by oxidative system ascorbate plus cupric chloride.
Valachová K, Kogan G, Gemeiner P, Soltés L. Interdiscip Toxicol. 2010 Mar; 3(1):26-34. Epub 2010 Mar 29.
Review Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species. [Glycobiology. 2011]
Review Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species.
Duan J, Kasper DL. Glycobiology. 2011 Apr; 21(4):401-9. Epub 2010 Oct 28.
Applications of electron spin resonance spectrometry for reactive oxygen species and reactive nitrogen species research. [J Clin Biochem Nutr. 2010]
Applications of electron spin resonance spectrometry for reactive oxygen species and reactive nitrogen species research.
Kohno M. J Clin Biochem Nutr. 2010 Jul; 47(1):1-11. Epub 2010 Jun 18.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Free radicals and inflammation: protection of synovial fluid by superoxide dismu...
Free radicals and inflammation: protection of synovial fluid by superoxide dismutase.
Science. 1974 Aug 9 ;185(4150):529-31.

PubMed
Mourning and depression: their similarities and differences.
Mourning and depression: their similarities and differences.
Can Psychiatr Assoc J. 1974 Jun ;19(3):309-12.

PubMed
Glucose-6-phosphate dehydrogenase (G-6-PD) Hamburg, a new variant with chronic n...
Glucose-6-phosphate dehydrogenase (G-6-PD) Hamburg, a new variant with chronic nonspherocytic haemolytic anaemia.
Eur J Clin Invest. 1974 Jun ;4(3):187-91.

PubMed
The anatomy and function of the proximal tibiofibular joint.
The anatomy and function of the proximal tibiofibular joint.
Clin Orthop Relat Res. 1974 Jun ;(101):186-91.

PubMed
The prediction of outcome in schizophrenia. II. Relationships between predictor ...
The prediction of outcome in schizophrenia. II. Relationships between predictor and outcome variables: a report from the WHO international pilot study of schizophrenia.
Arch Gen Psychiatry. 1974 Jul ;31(1):37-42.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Free radicals and inflammation: protection of synovial fluid by superoxide dismutase.

Abstract

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 88 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information