Atypical spherocytosis, a disease of spleen as wel...[Lancet. 1975]

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1: Lancet. 1975 Apr 26;1(7913):956-7. Links

Atypical spherocytosis, a disease of spleen as well as of red blood-cells.

Garwicz S.

It is proposed that atypical spherocytosis is a result of severe spherocytosis combined with splenic dysfunction. The spleen exercises a "conditioning" effect on the red blood-cell but is insufficient in the "culling" and "pitting" functions. As a result, a large population of severely damaged erythrocytes is circulating in the peripheral blood giving rise to atypical autohaemolysis.

PMID: 48127 [PubMed - indexed for MEDLINE]

Red cell survival studies in hereditary spherocytosis.
J Clin Invest. 1970 Apr; 49(4):666-72.

[J Clin Invest. 1970]
What happens to the microspherocytosis of hereditary spherocytosis in folate deficiency?
Clin Lab Haematol. 1988; 10(4):403-8.

[Clin Lab Haematol. 1988]
A splenunculus in hereditary spherocytosis.
Br J Haematol. 1968 Aug; 15(2):141-6.

[Br J Haematol. 1968]
Review[Clinical picture of spherocytosis: syndromes and diagnostic aspects]
Sangre (Barc). 1983; 28(3):330-40.

[Sangre (Barc). 1983]
ReviewHereditary spherocytosis revisited. Eighth annual Paul M. Aggeler Memorial Lecture. Delivered October 25, 1977, San Francisco General Hospital Medical Center.
West J Med. 1978 Jan; 128(1):35-45.

[West J Med. 1978]
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