Lancet. 1975 Apr 5;1(7910):775-7.

Metronidazole for Crohn's disease.

Abstract

Five patients with Crohn's disease for 4 months to 12 years were treated with metronidazole. Four of them improved after 2-4 weeks' treatment. In three of them corticosteroids and sulphasalazine could be withdrawn. One patient did not improve until 4 months of metronidazole treatment had passed and corticosteroids were reintroduced. In three patients metronidazole was discontinued after 4-6 months of treatment. Two of them had no signs or symptoms of relapse 3 and 6 months later. The third patient is free from symptoms but laboratory data indicate disease activity.

PMID:: 48003; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Elsevier Science

Medical

Crohn's Disease - MedlinePlus Health Information

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result. [Gastroenterology. 1982]
A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result.
Ursing B, Alm T, Bárány F, Bergelin I, Ganrot-Norlin K, Hoevels J, Huitfeldt B, Järnerot G, Krause U, Krook A, et al. Gastroenterology. 1982 Sep; 83(3):550-62.
Pharmacotherapy of inflammatory bowel disease. Part 2. Metronidazole. [Postgrad Med. 1983]
Pharmacotherapy of inflammatory bowel disease. Part 2. Metronidazole.
Frank MS, Brandt LJ, Bernstein LH. Postgrad Med. 1983 Dec; 74(6):155-7, 160.
Use of antibiotics in the treatment of active Crohn's disease: experience with metronidazole and ciprofloxacin. [Ital J Gastroenterol Hepatol. ...]
Use of antibiotics in the treatment of active Crohn's disease: experience with metronidazole and ciprofloxacin.
Prantera C, Berto E, Scribano ML, Falasco G. Ital J Gastroenterol Hepatol. 1998 Dec; 30(6):602-6.
Review Drug therapy of inflammatory bowel disease. [Pharmacotherapy. 1983]
Review Drug therapy of inflammatory bowel disease.
Sack DM, Peppercorn MA. Pharmacotherapy. 1983 May-Jun; 3(3):158-76.
Review Current status of drug therapy for inflammatory bowel disease. [Compr Ther. 1985]
Review Current status of drug therapy for inflammatory bowel disease.
Peppercorn MA. Compr Ther. 1985 Dec; 11(12):14-9.

See reviews... See all...

Cited by 13 PubMed Central articles

Review Antibiotic therapy for Crohn's disease: a review. [Can J Gastroenterol. 2006]
Review Antibiotic therapy for Crohn's disease: a review.
Lal S, Steinhart AH. Can J Gastroenterol. 2006 Oct; 20(10):651-5.
Risk factors for surgery and postoperative recurrence in Crohn's disease. [Ann Surg. 2000]
Risk factors for surgery and postoperative recurrence in Crohn's disease.
Bernell O, Lapidus A, Hellers G. Ann Surg. 2000 Jan; 231(1):38-45.
Faecal diversion for Crohn's colitis: a model to study the role of the faecal stream in the inflammatory process. [Gut. 1994]
Faecal diversion for Crohn's colitis: a model to study the role of the faecal stream in the inflammatory process.
Winslet MC, Allan A, Poxon V, Youngs D, Keighley MR. Gut. 1994 Feb; 35(2):236-42.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Metronidazole for Crohn's disease.
Metronidazole for Crohn's disease.
Lancet. 1975 Apr 5 ;1(7910):775-7.

PubMed
Ventilatory functions of normal children and young adults--Mexican-American, whi...
Ventilatory functions of normal children and young adults--Mexican-American, white, and black. I. Spirometry.
J Pediatr. 1979 Jul ;95(1):14-23.

PubMed
Growth of the second metacarpal width in Japanese and whites aged 7 to 12 years.
Growth of the second metacarpal width in Japanese and whites aged 7 to 12 years.
Kaibogaku Zasshi. 1973 Dec ;48(6):386-90.

PubMed
Postpartum mania in bipolar manic-depressive patients withdrawn from lithium car...
Postpartum mania in bipolar manic-depressive patients withdrawn from lithium carbonate.
J Nerv Ment Dis. 1979 Sep ;167(9):572-4.

PubMed
Ultrasound as a clinical tool in valvular heart disease.
Ultrasound as a clinical tool in valvular heart disease.
Cardiovasc Clin. 1973 ;5(2):219-46.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Metronidazole for Crohn's disease.

Abstract

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 13 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information