Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
J Physiol. 1973 Oct;234(2):443-7.

Presbyopia and the water content of the human crystalline lens.


1. The water content of the human crystallaline lens nucleus is 63.4% S.D. +/- 2.9%, and cortex 68.6% S.D. +/- 4.3%.2. Neither the total water content of the cortex, nor that of the nucleus show any significant changes with age, so ;sclerosis' of the lens due to loss of water is not a cause of presbyopia.3. The initial loss of water from the nucleus of the lens substance obtained by drying in vacuo at 20 degrees C for 2 hr is related to age (P = 0.05) and deformability (0.02 > P > 0.01).4. The lens fibres of the ageing nucleus have an increased resistance to deformation associated with a decrease in initial water loss. These characteristics can be explained by a common physical property of the fibres, namely increased adhesion to each other as the lens nucleus ages. The newly formed cortical fibres do not appear to show these changes.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk