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Ann Hum Genet. 1979 May;42(4):507-12.

The 'singles' method for segregation analysis under incomplete ascertainment.

Abstract

Li & Mantel (1968) proposed a simple new method of segregation analysis under complete ascertainment. This paper shows that, with a slight modification, the method is also valid under incomplete ascertainment. The assumptions concerning ascertainment are discussed and the method compared with the maximum likelihood method and Weinberg's proband method.

PMID:
475337
[PubMed - indexed for MEDLINE]
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