Science. 1979 Sep 14;205(4411):1163-4.

Plasma beta-endorphin immunoreactivity in schizophrenia.

Abstract

Plasma beta-endorphin-like immunoreactivity was measured by a method that was equally sensitive to beta-endorphin and [Leu5]-beta-endorphin. Immunoreactivity in 98 schizophrenic patients did not differ greatly from that in 42 normal subjects. No immunoreactivity was detectable in dialyzates from first-time hemodialysis of eight nonpsychotic renal patients and nine schizophrenic patients. These results are not compatible with recent reports of extremely high concentrations of [Leu5]-beta-endorphin in hemodialyzates from schizophrenic patients.

PMID:: 472735; [PubMed - indexed for MEDLINE]

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Research Support, U.S. Gov't, P.H.S.

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Endorphins

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