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Science. 1973 Mar 9;179(4077):1011-4.

Opiate receptor: demonstration in nervous tissue.

Abstract

Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig intestine. Competition for the opiate receptor by various opiates and their antagonists closely parallels their pharmacological potency. The opiate receptor is confined to nervous tissue.

PMID:
4687585
[PubMed - indexed for MEDLINE]
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