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Science. 1972 Dec 22;178(4067):1290-2.

Evidence for active immunity to morphine in mice.

Abstract

The serum from mice actively immunized with a morphine immunogen contained antibodies that could bind dihydromorphine. Morphine effects were diminished in these "immunized" mice, and the concentration of morphine in their plasma was altered.

PMID:
4640066
[PubMed - indexed for MEDLINE]
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