Abstract
Synovial fluid lymphocytes from patients with rheumatoid arthritis were effectively stimulated by B cell mitogens, such as pokeweed mitogen (PWM) and lipopolysaccharides (LPS), but their response to T cell mitogen, phytohaemagglutinin (PHA), was poor and no stimulation was observed in the presence of specific antigens, purified protein derivative (PPD) or Veillonella alcalescens sonicate.
MeSH terms
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Adult
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Aged
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Arthritis, Rheumatoid / immunology
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B-Lymphocytes / immunology
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Female
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Fluorescent Antibody Technique
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Humans
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Lectins / pharmacology*
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Lipopolysaccharides / pharmacology
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Lymphocyte Activation / drug effects
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Lymphocytes / drug effects*
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Male
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Middle Aged
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Mitogens / pharmacology
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Synovial Fluid / immunology*
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T-Lymphocytes / immunology
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Tuberculin / pharmacology
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Veillonella
Substances
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Lectins
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Lipopolysaccharides
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Mitogens
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Tuberculin