Abstract
OPTIMAL CONDITIONS FOR PRODUCING CONSISTENT YIELDS OF ANTIMYCIN A IN CHEMICALLY DEFINED MEDIUM INCLUDED: (i) initial pH of 6.8 to 7.1; (ii) no iron supplementation; (iii) 2 g of dl-tryptophan per liter; and antibiotic extraction after 7 to 9 days of growth.
MeSH terms
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Antimycin A / biosynthesis*
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Culture Media
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Hydrogen-Ion Concentration
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Iron / pharmacology
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Streptomyces / metabolism*
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Streptomyces antibioticus / drug effects
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Streptomyces antibioticus / metabolism
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Time Factors
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Tryptophan / pharmacology
Substances
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Culture Media
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Antimycin A
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Tryptophan
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Iron